BDBM50425334 CHEMBL2315874

SMILES: Clc1ccc2oc(nc2c1)N1CCC(CC1)S(=O)(=O)NC1CCCC1

InChI Key: InChIKey=HPWJOWKSDZBHEL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50425334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Homo sapiens (Human))	BDBM50425334 (CHEMBL2315874) Show SMILES Clc1ccc2oc(nc2c1)N1CCC(CC1)S(=O)(=O)NC1CCCC1 Show InChI InChI=1S/C17H22ClN3O3S/c18-12-5-6-16-15(11-12)19-17(24-16)21-9-7-14(8-10-21)25(22,23)20-13-3-1-2-4-13/h5-6,11,13-14,20H,1-4,7-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIA				Bioorg Med Chem Lett 23: 907-11 (2013) Article DOI: 10.1016/j.bmcl.2012.10.040 BindingDB Entry DOI: 10.7270/Q2Z3210H
					More data for this Ligand-Target Pair