null

SMILES: CN(c1ncccc1CNc1ccnc2[nH]ccc12)S(C)(=O)=O

InChI Key: InChIKey=UKJRNMSJORFXBN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50425669 (CHEMBL2315574) Show SMILES CN(c1ncccc1CNc1ccnc2[nH]ccc12)S(C)(=O)=O Show InChI InChI=1S/C15H17N5O2S/c1-20(23(2,21)22)15-11(4-3-7-18-15)10-19-13-6-9-17-14-12(13)5-8-16-14/h3-9H,10H2,1-2H3,(H2,16,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Research Curated by ChEMBL					Assay Description Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysis				J Med Chem 56: 1160-70 (2013) Article DOI: 10.1021/jm3016014 BindingDB Entry DOI: 10.7270/Q2GT5PGP
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50425669 (CHEMBL2315574) Show SMILES CN(c1ncccc1CNc1ccnc2[nH]ccc12)S(C)(=O)=O Show InChI InChI=1S/C15H17N5O2S/c1-20(23(2,21)22)15-11(4-3-7-18-15)10-19-13-6-9-17-14-12(13)5-8-16-14/h3-9H,10H2,1-2H3,(H2,16,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.76E+3	n/a	n/a	n/a	n/a	n/a
Merck Serono Research Curated by ChEMBL					Assay Description Binding affinity to FAK (unknown origin) by surface plasmon resonance analysis				J Med Chem 56: 1160-70 (2013) Article DOI: 10.1021/jm3016014 BindingDB Entry DOI: 10.7270/Q2GT5PGP
					More data for this Ligand-Target Pair