BDBM50427107 CHEMBL2322877

SMILES: CC(C)Oc1cc(ccc1Cl)N1CCN(CC1)C(=O)Cn1nc(c(Cl)c1C)C(F)(F)F

InChI Key: InChIKey=FOCDXZMZPHBJOJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50427107 (CHEMBL2322877) Show SMILES CC(C)Oc1cc(ccc1Cl)N1CCN(CC1)C(=O)Cn1nc(c(Cl)c1C)C(F)(F)F Show InChI InChI=1S/C20H23Cl2F3N4O2/c1-12(2)31-16-10-14(4-5-15(16)21)27-6-8-28(9-7-27)17(30)11-29-13(3)18(22)19(26-29)20(23,24)25/h4-5,10,12H,6-9,11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-CCL3/MIP-1alpha from CCR1 in human THP1 cells				Bioorg Med Chem Lett 23: 1228-31 (2013) Article DOI: 10.1016/j.bmcl.2013.01.005 BindingDB Entry DOI: 10.7270/Q2NZ88Z2
					More data for this Ligand-Target Pair