BDBM50427455 CHEMBL2326951

SMILES: CN1CCN(CC1)c1ncc(cn1)-c1csc2c1oc(cc2=O)N1CCOCC1

InChI Key: InChIKey=OJYGAVUXIZEZOW-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50427455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50427455 (CHEMBL2326951) Show SMILES CN1CCN(CC1)c1ncc(cn1)-c1csc2c1oc(cc2=O)N1CCOCC1 Show InChI InChI=1S/C20H23N5O3S/c1-23-2-4-25(5-3-23)20-21-11-14(12-22-20)15-13-29-19-16(26)10-17(28-18(15)19)24-6-8-27-9-7-24/h10-13H,2-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Arizona Curated by ChEMBL					Assay Description Inhibition of PI3K p110gamma (unknown origin)				J Med Chem 56: 1922-39 (2013) Article DOI: 10.1021/jm301522m BindingDB Entry DOI: 10.7270/Q2Z89DR9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50427455 (CHEMBL2326951) Show SMILES CN1CCN(CC1)c1ncc(cn1)-c1csc2c1oc(cc2=O)N1CCOCC1 Show InChI InChI=1S/C20H23N5O3S/c1-23-2-4-25(5-3-23)20-21-11-14(12-22-20)15-13-29-19-16(26)10-17(28-18(15)19)24-6-8-27-9-7-24/h10-13H,2-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	433	n/a	n/a	n/a	n/a	n/a	n/a
The University of Arizona Curated by ChEMBL					Assay Description Inhibition of PI3K p110beta (unknown origin)				J Med Chem 56: 1922-39 (2013) Article DOI: 10.1021/jm301522m BindingDB Entry DOI: 10.7270/Q2Z89DR9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50427455 (CHEMBL2326951) Show SMILES CN1CCN(CC1)c1ncc(cn1)-c1csc2c1oc(cc2=O)N1CCOCC1 Show InChI InChI=1S/C20H23N5O3S/c1-23-2-4-25(5-3-23)20-21-11-14(12-22-20)15-13-29-19-16(26)10-17(28-18(15)19)24-6-8-27-9-7-24/h10-13H,2-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
The University of Arizona Curated by ChEMBL					Assay Description Inhibition of PI3K p110delta (unknown origin)				J Med Chem 56: 1922-39 (2013) Article DOI: 10.1021/jm301522m BindingDB Entry DOI: 10.7270/Q2Z89DR9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50427455 (CHEMBL2326951) Show SMILES CN1CCN(CC1)c1ncc(cn1)-c1csc2c1oc(cc2=O)N1CCOCC1 Show InChI InChI=1S/C20H23N5O3S/c1-23-2-4-25(5-3-23)20-21-11-14(12-22-20)15-13-29-19-16(26)10-17(28-18(15)19)24-6-8-27-9-7-24/h10-13H,2-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	345	n/a	n/a	n/a	n/a	n/a	n/a
The University of Arizona Curated by ChEMBL					Assay Description Inhibition of PI3K p110alpha (unknown origin)				J Med Chem 56: 1922-39 (2013) Article DOI: 10.1021/jm301522m BindingDB Entry DOI: 10.7270/Q2Z89DR9
					More data for this Ligand-Target Pair