BDBM50427520 CHEMBL2322262

SMILES: Cc1c(CCC(=O)Nc2cccc(O)c2)c(=O)oc2c(C)c3oc4CCCCc4c3cc12

InChI Key: InChIKey=YIIREXBIWWXISD-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B (NF-kB) (Homo sapiens (Human))	BDBM50427520 (CHEMBL2322262) Show SMILES Cc1c(CCC(=O)Nc2cccc(O)c2)c(=O)oc2c(C)c3oc4CCCCc4c3cc12 Show InChI InChI=1S/C26H25NO5/c1-14-18(10-11-23(29)27-16-6-5-7-17(28)12-16)26(30)32-24-15(2)25-21(13-20(14)24)19-8-3-4-9-22(19)31-25/h5-7,12-13,28H,3-4,8-11H2,1-2H3,(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.00E+5	n/a	n/a	n/a	n/a
Universit£ degli Studi di Padova Curated by ChEMBL					Assay Description Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...				J Med Chem 56: 1830-42 (2013) Article DOI: 10.1021/jm3009647 BindingDB Entry DOI: 10.7270/Q2TH8P10
					More data for this Ligand-Target Pair