BDBM50428326 CHEMBL2338393

SMILES: Cc1cc(no1)-c1nc(NC[C@H]2CCC[C@H](O2)c2ccc(cc2)C(F)(F)F)c(C)c(n1)C(=O)N1CCC(CC1)N[C@@H]1CCOC[C@@H]1F

InChI Key: InChIKey=CSTRIVMEIYPLGJ-ASUDMDKOSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50428326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50428326 (CHEMBL2338393) Show SMILES Cc1cc(no1)-c1nc(NC[C@H]2CCC[C@H](O2)c2ccc(cc2)C(F)(F)F)c(C)c(n1)C(=O)N1CCC(CC1)N[C@@H]1CCOC[C@@H]1F |r| Show InChI InChI=1S/C33H40F4N6O4/c1-19-16-27(42-47-19)31-40-29(32(44)43-13-10-23(11-14-43)39-26-12-15-45-18-25(26)34)20(2)30(41-31)38-17-24-4-3-5-28(46-24)21-6-8-22(9-7-21)33(35,36)37/h6-9,16,23-26,28,39H,3-5,10-15,17-18H2,1-2H3,(H,38,40,41)/t24-,25+,26-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]MCP1 from CCR2 in human THP1 cell membranes after 8 hrs by scintillation counting analysis				ACS Med Chem Lett 4: 371-2 (2013) Article DOI: 10.1021/ml400055e BindingDB Entry DOI: 10.7270/Q2B859FX
					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50428326 (CHEMBL2338393) Show SMILES Cc1cc(no1)-c1nc(NC[C@H]2CCC[C@H](O2)c2ccc(cc2)C(F)(F)F)c(C)c(n1)C(=O)N1CCC(CC1)N[C@@H]1CCOC[C@@H]1F |r| Show InChI InChI=1S/C33H40F4N6O4/c1-19-16-27(42-47-19)31-40-29(32(44)43-13-10-23(11-14-43)39-26-12-15-45-18-25(26)34)20(2)30(41-31)38-17-24-4-3-5-28(46-24)21-6-8-22(9-7-21)33(35,36)37/h6-9,16,23-26,28,39H,3-5,10-15,17-18H2,1-2H3,(H,38,40,41)/t24-,25+,26-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]RANTES from human CCR5 expressed in CHO cell membranes coexpressing Gal6 after 6 hrs by scintillation counting analysis				ACS Med Chem Lett 4: 371-2 (2013) Article DOI: 10.1021/ml400055e BindingDB Entry DOI: 10.7270/Q2B859FX
					More data for this Ligand-Target Pair