BDBM50428677 CHEMBL2332693

SMILES: C[C@@H]1CC[C@@H](CO[C@H]2CC[C@@H](CC2)C(O)=O)N1C(=O)Cc1ccc2nc(Nc3cc(F)ccc3C)oc2c1F

InChI Key: InChIKey=WALBDOUQZAEZGC-RPHTVSPISA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50428677   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibronectin receptor beta/Integrin alpha-4 (Homo sapiens (Human))	BDBM50428677 (CHEMBL2332693) Show SMILES C[C@@H]1CC[C@@H](CO[C@H]2CC[C@@H](CC2)C(O)=O)N1C(=O)Cc1ccc2nc(Nc3cc(F)ccc3C)oc2c1F |r,wU:4.4,10.13,wD:1.0,7.6,(15.99,-39.89,;17.35,-40.62,;18.81,-40.13,;19.73,-41.36,;18.83,-42.62,;19.58,-43.96,;21.12,-43.98,;21.87,-45.33,;21.07,-46.65,;21.82,-47.99,;23.36,-48.02,;24.15,-46.7,;23.4,-45.35,;24.1,-49.37,;25.64,-49.4,;23.31,-50.69,;17.35,-42.15,;16.12,-43.07,;16.12,-44.61,;14.78,-42.3,;13.45,-43.08,;13.45,-44.63,;12.12,-45.4,;10.78,-44.63,;9.31,-45.1,;8.42,-43.85,;6.88,-43.85,;6.11,-42.51,;6.89,-41.19,;6.12,-39.85,;6.9,-38.52,;4.58,-39.85,;3.81,-41.19,;4.58,-42.52,;3.81,-43.85,;9.32,-42.61,;10.79,-43.09,;12.11,-42.32,;12.11,-40.78,)| Show InChI InChI=1S/C29H33F2N3O5/c1-16-3-8-20(30)14-24(16)33-29-32-23-12-7-19(26(31)27(23)39-29)13-25(35)34-17(2)4-9-21(34)15-38-22-10-5-18(6-11-22)28(36)37/h3,7-8,12,14,17-18,21-22H,4-6,9-11,13,15H2,1-2H3,(H,32,33)(H,36,37)/t17-,18-,21+,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of Europium-labeled human VCAM1 binding to human VLA4 expressed in Chinese hamster 4B4 cells incubated for 60 mins in presence of 3% HSA b...				Bioorg Med Chem 21: 42-61 (2012) Article DOI: 10.1016/j.bmc.2012.11.003 BindingDB Entry DOI: 10.7270/Q2DV1M7X
					More data for this Ligand-Target Pair
Fibronectin receptor beta/Integrin alpha-4 (Homo sapiens (Human))	BDBM50428677 (CHEMBL2332693) Show SMILES C[C@@H]1CC[C@@H](CO[C@H]2CC[C@@H](CC2)C(O)=O)N1C(=O)Cc1ccc2nc(Nc3cc(F)ccc3C)oc2c1F |r,wU:4.4,10.13,wD:1.0,7.6,(15.99,-39.89,;17.35,-40.62,;18.81,-40.13,;19.73,-41.36,;18.83,-42.62,;19.58,-43.96,;21.12,-43.98,;21.87,-45.33,;21.07,-46.65,;21.82,-47.99,;23.36,-48.02,;24.15,-46.7,;23.4,-45.35,;24.1,-49.37,;25.64,-49.4,;23.31,-50.69,;17.35,-42.15,;16.12,-43.07,;16.12,-44.61,;14.78,-42.3,;13.45,-43.08,;13.45,-44.63,;12.12,-45.4,;10.78,-44.63,;9.31,-45.1,;8.42,-43.85,;6.88,-43.85,;6.11,-42.51,;6.89,-41.19,;6.12,-39.85,;6.9,-38.52,;4.58,-39.85,;3.81,-41.19,;4.58,-42.52,;3.81,-43.85,;9.32,-42.61,;10.79,-43.09,;12.11,-42.32,;12.11,-40.78,)| Show InChI InChI=1S/C29H33F2N3O5/c1-16-3-8-20(30)14-24(16)33-29-32-23-12-7-19(26(31)27(23)39-29)13-25(35)34-17(2)4-9-21(34)15-38-22-10-5-18(6-11-22)28(36)37/h3,7-8,12,14,17-18,21-22H,4-6,9-11,13,15H2,1-2H3,(H,32,33)(H,36,37)/t17-,18-,21+,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of Europium-labeled human VCAM1 binding to human VLA4 expressed in Chinese hamster 4B4 cells incubated for 60 mins by fluorometric assay				Bioorg Med Chem 21: 42-61 (2012) Article DOI: 10.1016/j.bmc.2012.11.003 BindingDB Entry DOI: 10.7270/Q2DV1M7X
					More data for this Ligand-Target Pair