BDBM50429108 CHEMBL2335779

SMILES: CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1cccc(F)c1F

InChI Key: InChIKey=FPGORJYWLMAUBV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50429108 (CHEMBL2335779) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1cccc(F)c1F Show InChI InChI=1S/C17H13F2N3O4S/c1-27(25,26)22-12-7-2-4-9-14(23)8-13(20-16(9)12)17(24)21-11-6-3-5-10(18)15(11)19/h2-8,22H,1H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair