BDBM50429351 CHEMBL2334928

SMILES: COc1ccc(\C=C(\C(O)=O)c2ccc3ccccc3c2)cc1OC

InChI Key: InChIKey=JEEIUUUYJJGNLS-WOJGMQOQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3) (Homo sapiens (Human))	BDBM50429351 (CHEMBL2334928) Show SMILES COc1ccc(\C=C(\C(O)=O)c2ccc3ccccc3c2)cc1OC Show InChI InChI=1S/C21H18O4/c1-24-19-10-7-14(12-20(19)25-2)11-18(21(22)23)17-9-8-15-5-3-4-6-16(15)13-17/h3-13H,1-2H3,(H,22,23)/b18-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of recombinant AKR1C3 (unknown origin) assessed as decrease in oxidation of 1-acenaphthenol substrate by spectrophotometric analysis				Eur J Med Chem 62: 89-97 (2013) Article DOI: 10.1016/j.ejmech.2012.12.045 BindingDB Entry DOI: 10.7270/Q2BR8TH0
					More data for this Ligand-Target Pair