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SMILES: Nc1ncc2CCc3[nH]c4ccc(Cl)cc4c3-c2n1

InChI Key: InChIKey=KAQABGOWPUBBDM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429622   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase 14


(Homo sapiens (Human))		BDBM50429622
PNG
(CHEMBL2334581)
Show SMILES Nc1ncc2CCc3[nH]c4ccc(Cl)cc4c3-c2n1
Show InChI InChI=1S/C14H11ClN4/c15-8-2-4-10-9(5-8)12-11(18-10)3-1-7-6-17-14(16)19-13(7)12/h2,4-6,18H,1,3H2,(H2,16,17,19)
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KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assay

Bioorg Med Chem Lett 23: 1238-44 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.012
BindingDB Entry DOI: 10.7270/Q2J967RQ
More data for this
Ligand-Target Pair