Found 3 hits for monomerid = 50430743 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Nitric oxide synthase, endothelial
(Homo sapiens (Human)) | BDBM50430743
(CHEMBL2333953)Show SMILES NC(=Nc1ccc(CCNCCc2cccc(Cl)c2)cc1)c1cccs1 |w:2.2| Show InChI InChI=1S/C21H22ClN3S/c22-18-4-1-3-17(15-18)11-13-24-12-10-16-6-8-19(9-7-16)25-21(23)20-5-2-14-26-20/h1-9,14-15,24H,10-13H2,(H2,23,25) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Inhibition of human eNOS |
J Med Chem 56: 3121-47 (2013)
Article DOI: 10.1021/jm3015926 BindingDB Entry DOI: 10.7270/Q23T9JKG |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50430743
(CHEMBL2333953)Show SMILES NC(=Nc1ccc(CCNCCc2cccc(Cl)c2)cc1)c1cccs1 |w:2.2| Show InChI InChI=1S/C21H22ClN3S/c22-18-4-1-3-17(15-18)11-13-24-12-10-16-6-8-19(9-7-16)25-21(23)20-5-2-14-26-20/h1-9,14-15,24H,10-13H2,(H2,23,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Inhibition of human nNOS |
J Med Chem 56: 3121-47 (2013)
Article DOI: 10.1021/jm3015926 BindingDB Entry DOI: 10.7270/Q23T9JKG |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50430743
(CHEMBL2333953)Show SMILES NC(=Nc1ccc(CCNCCc2cccc(Cl)c2)cc1)c1cccs1 |w:2.2| Show InChI InChI=1S/C21H22ClN3S/c22-18-4-1-3-17(15-18)11-13-24-12-10-16-6-8-19(9-7-16)25-21(23)20-5-2-14-26-20/h1-9,14-15,24H,10-13H2,(H2,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Inhibition of human iNOS |
J Med Chem 56: 3121-47 (2013)
Article DOI: 10.1021/jm3015926 BindingDB Entry DOI: 10.7270/Q23T9JKG |
More data for this Ligand-Target Pair | |