BDBM50431905 CHEMBL2347810

SMILES: CS(=O)(=O)c1ccc(cc1)-c1ccc2c(N3CCC3)c(cnc2c1)C#N

InChI Key: InChIKey=LWWUWOBXMWNAFL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431905   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM50431905 (CHEMBL2347810) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2c(N3CCC3)c(cnc2c1)C#N Show InChI InChI=1S/C20H17N3O2S/c1-26(24,25)17-6-3-14(4-7-17)15-5-8-18-19(11-15)22-13-16(12-21)20(18)23-9-2-10-23/h3-8,11,13H,2,9-10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of wild type GST-tagged LRRK2 (970-2527 amino acids)(unknown origin) assessed as inhibition of LRRKtide phosphorylation by HTRF assay				Bioorg Med Chem Lett 23: 1974-7 (2013) Article DOI: 10.1016/j.bmcl.2013.02.041 BindingDB Entry DOI: 10.7270/Q2FQ9XZ1
					More data for this Ligand-Target Pair