BDBM50432885 CHEMBL2376658

SMILES: CNC(=O)c1ccc(NC(=O)c2cc(O[C@H](C)c3c(Cl)ccc(F)c3Cl)c[nH]c2=O)cc1F

InChI Key: InChIKey=VAYGNSRWLDCVEQ-SNVBAGLBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50432885 (CHEMBL2376658) Show SMILES CNC(=O)c1ccc(NC(=O)c2cc(O[C@H](C)c3c(Cl)ccc(F)c3Cl)c[nH]c2=O)cc1F |r| Show InChI InChI=1S/C22H17Cl2F2N3O4/c1-10(18-15(23)5-6-16(25)19(18)24)33-12-8-14(21(31)28-9-12)22(32)29-11-3-4-13(17(26)7-11)20(30)27-2/h3-10H,1-2H3,(H,27,30)(H,28,31)(H,29,32)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of c-MET (unknown origin) after 60 mins by ELISA				Bioorg Med Chem Lett 23: 2408-13 (2013) Article DOI: 10.1016/j.bmcl.2013.02.037 BindingDB Entry DOI: 10.7270/Q2TQ62XH
					More data for this Ligand-Target Pair