BDBM50434559 CHEMBL2386001

SMILES: C1O[B-](c2ccccc2)(c2ccccc2)[n+]2ccccc12

InChI Key: InChIKey=UWSCJSOSXINLMD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 6 (Homo sapiens (Human))	BDBM50434559 (CHEMBL2386001) Show SMILES C1O[B-](c2ccccc2)(c2ccccc2)[n+]2ccccc12 Show InChI InChI=1S/C18H16BNO/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)20-14-8-7-13-18(20)15-21-19/h1-14H,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assay				Bioorg Med Chem 21: 3202-13 (2013) Article DOI: 10.1016/j.bmc.2013.03.037 BindingDB Entry DOI: 10.7270/Q2KK9D6T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 6 (Homo sapiens (Human))	BDBM50434559 (CHEMBL2386001) Show SMILES C1O[B-](c2ccccc2)(c2ccccc2)[n+]2ccccc12 Show InChI InChI=1S/C18H16BNO/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)20-14-8-7-13-18(20)15-21-19/h1-14H,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assay				Bioorg Med Chem 21: 3202-13 (2013) Article DOI: 10.1016/j.bmc.2013.03.037 BindingDB Entry DOI: 10.7270/Q2KK9D6T
					More data for this Ligand-Target Pair