BDBM50434723 CHEMBL2385203

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5cccc(F)c5)c5ccccc5c4=O)cc3F)ccnc2cc1OCCCN1CCCCC1

InChI Key: InChIKey=LGOXXSVEWLLEKB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434723   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50434723 (CHEMBL2385203) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5cccc(F)c5)c5ccccc5c4=O)cc3F)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C39H35F2N5O5/c1-49-35-23-29-31(24-36(35)50-20-8-19-45-17-5-2-6-18-45)42-16-15-33(29)51-34-14-13-26(22-30(34)41)43-39(48)37-38(47)28-11-3-4-12-32(28)46(44-37)27-10-7-9-25(40)21-27/h3-4,7,9-16,21-24H,2,5-6,8,17-20H2,1H3,(H,43,48)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 21: 2843-55 (2013) Article DOI: 10.1016/j.bmc.2013.04.013 BindingDB Entry DOI: 10.7270/Q25D8T6Z
					More data for this Ligand-Target Pair