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SMILES: Clc1ccc(Nc2nccc(n2)-c2ccc3OCOc3c2)cc1

InChI Key: InChIKey=LZUVHLORMNUQJL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50435483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase CLK2 (Homo sapiens (Human))	BDBM50435483 (CHEMBL1899640) Show SMILES Clc1ccc(Nc2nccc(n2)-c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C17H12ClN3O2/c18-12-2-4-13(5-3-12)20-17-19-8-7-14(21-17)11-1-6-15-16(9-11)23-10-22-15/h1-9H,10H2,(H,19,20,21)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of CLK2 (unknown origin)				Bioorg Med Chem Lett 23: 3654-61 (2013) Article DOI: 10.1016/j.bmcl.2013.02.096 BindingDB Entry DOI: 10.7270/Q2M90B2B
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK4 (Homo sapiens (Human))	BDBM50435483 (CHEMBL1899640) Show SMILES Clc1ccc(Nc2nccc(n2)-c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C17H12ClN3O2/c18-12-2-4-13(5-3-12)20-17-19-8-7-14(21-17)11-1-6-15-16(9-11)23-10-22-15/h1-9H,10H2,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of CLK4 (unknown origin)				Bioorg Med Chem Lett 23: 3654-61 (2013) Article DOI: 10.1016/j.bmcl.2013.02.096 BindingDB Entry DOI: 10.7270/Q2M90B2B
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50435483 (CHEMBL1899640) Show SMILES Clc1ccc(Nc2nccc(n2)-c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C17H12ClN3O2/c18-12-2-4-13(5-3-12)20-17-19-8-7-14(21-17)11-1-6-15-16(9-11)23-10-22-15/h1-9H,10H2,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of CLK1 (unknown origin)				Bioorg Med Chem Lett 23: 3654-61 (2013) Article DOI: 10.1016/j.bmcl.2013.02.096 BindingDB Entry DOI: 10.7270/Q2M90B2B
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50435483 (CHEMBL1899640) Show SMILES Clc1ccc(Nc2nccc(n2)-c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C17H12ClN3O2/c18-12-2-4-13(5-3-12)20-17-19-8-7-14(21-17)11-1-6-15-16(9-11)23-10-22-15/h1-9H,10H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	273	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of DYRK1A (unknown origin)				Bioorg Med Chem Lett 23: 3654-61 (2013) Article DOI: 10.1016/j.bmcl.2013.02.096 BindingDB Entry DOI: 10.7270/Q2M90B2B
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50435483 (CHEMBL1899640) Show SMILES Clc1ccc(Nc2nccc(n2)-c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C17H12ClN3O2/c18-12-2-4-13(5-3-12)20-17-19-8-7-14(21-17)11-1-6-15-16(9-11)23-10-22-15/h1-9H,10H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of DYRK1A (unknown origin) by bioluminescence assay				Bioorg Med Chem Lett 23: 3654-61 (2013) Article DOI: 10.1016/j.bmcl.2013.02.096 BindingDB Entry DOI: 10.7270/Q2M90B2B
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK4 (Homo sapiens (Human))	BDBM50435483 (CHEMBL1899640) Show SMILES Clc1ccc(Nc2nccc(n2)-c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C17H12ClN3O2/c18-12-2-4-13(5-3-12)20-17-19-8-7-14(21-17)11-1-6-15-16(9-11)23-10-22-15/h1-9H,10H2,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of CLK4 (unknown origin) by bioluminescence assay				Bioorg Med Chem Lett 23: 3654-61 (2013) Article DOI: 10.1016/j.bmcl.2013.02.096 BindingDB Entry DOI: 10.7270/Q2M90B2B
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50435483 (CHEMBL1899640) Show SMILES Clc1ccc(Nc2nccc(n2)-c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C17H12ClN3O2/c18-12-2-4-13(5-3-12)20-17-19-8-7-14(21-17)11-1-6-15-16(9-11)23-10-22-15/h1-9H,10H2,(H,19,20,21)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	884	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of DYRK1B (unknown origin)				Bioorg Med Chem Lett 23: 3654-61 (2013) Article DOI: 10.1016/j.bmcl.2013.02.096 BindingDB Entry DOI: 10.7270/Q2M90B2B
					More data for this Ligand-Target Pair