BDBM50435556 CHEMBL2392815

SMILES: Cc1cncn1CCCNC(=S)Nc1ccc2OCCNc2c1

InChI Key: InChIKey=VZEQJIFWBFCQBU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50435556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminyl Cyclase (Homo sapiens (Human))	BDBM50435556 (CHEMBL2392815) Show SMILES Cc1cncn1CCCNC(=S)Nc1ccc2OCCNc2c1 Show InChI InChI=1S/C16H21N5OS/c1-12-10-17-11-21(12)7-2-5-19-16(23)20-13-3-4-15-14(9-13)18-6-8-22-15/h3-4,9-11,18H,2,5-8H2,1H3,(H2,19,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	492	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of human glutaminyl cyclase expressed in HEK293 cells using L-glutaminyl-beta-naphthylamine as substrate after 1 hr by fluorometric analys...				Bioorg Med Chem 21: 3821-30 (2013) Article DOI: 10.1016/j.bmc.2013.04.005 BindingDB Entry DOI: 10.7270/Q2BR8TJF
					More data for this Ligand-Target Pair