BDBM50436369 CHEMBL2396731

SMILES: OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=RUGWCZFSYXQKMP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50436369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM50436369 (CHEMBL2396731) Show SMILES OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C23H14O5/c1-2-17-18-12-19(23(25)26)20(24)13-21(18)28-22(17)14-8-10-16(11-9-14)27-15-6-4-3-5-7-15/h1,3-13,24H,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...				J Med Chem 56: 4990-5008 (2013) Article DOI: 10.1021/jm400248c BindingDB Entry DOI: 10.7270/Q2N017XW
					More data for this Ligand-Target Pair