BDBM50437292 CHEMBL2407484

SMILES: OC(=O)CSc1nnc(-c2ccc(O)cc2)n1-c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=ZGNMNPREZMHJOX-UHFFFAOYSA-N

Data: 1 Kd

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50437292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50437292 (CHEMBL2407484) Show SMILES OC(=O)CSc1nnc(-c2ccc(O)cc2)n1-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H11Cl2N3O3S/c17-12-6-3-10(7-13(12)18)21-15(9-1-4-11(22)5-2-9)19-20-16(21)25-8-14(23)24/h1-7,22H,8H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.33E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...				ACS Med Chem Lett 4: 601-605 (2013) Article DOI: 10.1021/ml400032y BindingDB Entry DOI: 10.7270/Q22N53PW
					More data for this Ligand-Target Pair