BDBM50437421 CHEMBL2409018

SMILES: CCCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1c[nH]c2ccccc12

InChI Key: InChIKey=TXDIARVDRHYBED-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50437421   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50437421 (CHEMBL2409018) Show SMILES CCCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C26H26N6OS/c1-3-4-10-22-20(25(33)28-15-18-14-27-21-9-6-5-8-19(18)21)16-30-32(22)26-29-13-17(2)24(31-26)23-11-7-12-34-23/h5-9,11-14,16,27H,3-4,10,15H2,1-2H3,(H,28,33)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay				ACS Med Chem Lett 4: 790-4 (2013) Article DOI: 10.1021/ml400186z BindingDB Entry DOI: 10.7270/Q24J0GHW
					More data for this Ligand-Target Pair