BDBM50438082 CHEMBL2409756

SMILES: OC12CC3CC(C1)CC(C3)(C2)N=C1NS(=O)(=O)[C@@H]2CCCC[C@@H]2O1

InChI Key: InChIKey=AHEKEXPSDHXIPA-GKNBTTNJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50438082 (CHEMBL2409756) Show SMILES OC12CC3CC(C1)CC(C3)(C2)N=C1NS(=O)(=O)[C@@H]2CCCC[C@@H]2O1 |r,w:11.13,THB:10:1:4:9.8.7,10:8:2.1.6:4,0:1:4:9.8.7,7:8:2:6.5.4,7:5:2:9.10.8,TEB:11:8:2:6.5.4,11:8:2.1.6:4| Show InChI InChI=1S/C17H26N2O4S/c20-17-8-11-5-12(9-17)7-16(6-11,10-17)18-15-19-24(21,22)14-4-2-1-3-13(14)23-15/h11-14,20H,1-10H2,(H,18,19)/t11?,12?,13-,14+,16?,17?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1				Bioorg Med Chem Lett 23: 4685-91 (2013) Article DOI: 10.1016/j.bmcl.2013.05.102 BindingDB Entry DOI: 10.7270/Q2BV7J2H
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50438082 (CHEMBL2409756) Show SMILES OC12CC3CC(C1)CC(C3)(C2)N=C1NS(=O)(=O)[C@@H]2CCCC[C@@H]2O1 |r,w:11.13,THB:10:1:4:9.8.7,10:8:2.1.6:4,0:1:4:9.8.7,7:8:2:6.5.4,7:5:2:9.10.8,TEB:11:8:2:6.5.4,11:8:2.1.6:4| Show InChI InChI=1S/C17H26N2O4S/c20-17-8-11-5-12(9-17)7-16(6-11,10-17)18-15-19-24(21,22)14-4-2-1-3-13(14)23-15/h11-14,20H,1-10H2,(H,18,19)/t11?,12?,13-,14+,16?,17?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1				Bioorg Med Chem Lett 23: 4685-91 (2013) Article DOI: 10.1016/j.bmcl.2013.05.102 BindingDB Entry DOI: 10.7270/Q2BV7J2H
					More data for this Ligand-Target Pair