BDBM50438170 CHEMBL2407437

SMILES: Nc1nc(nn1C(=O)c1ccc(Cl)cc1Cl)-c1cccnc1

InChI Key: InChIKey=DHKRQDRQUQSWOD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kallikrein 7 (Homo sapiens (Human))	BDBM50438170 (CHEMBL2407437) Show SMILES Nc1nc(nn1C(=O)c1ccc(Cl)cc1Cl)-c1cccnc1 Show InChI InChI=1S/C14H9Cl2N5O/c15-9-3-4-10(11(16)6-9)13(22)21-14(17)19-12(20-21)8-2-1-5-18-7-8/h1-7H,(H2,17,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC) Curated by ChEMBL					Assay Description Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assay				Bioorg Med Chem Lett 23: 4547-51 (2013) Article DOI: 10.1016/j.bmcl.2013.06.039 BindingDB Entry DOI: 10.7270/Q23B61JV
					More data for this Ligand-Target Pair
Kallikrein 5 (Homo sapiens (Human))	BDBM50438170 (CHEMBL2407437) Show SMILES Nc1nc(nn1C(=O)c1ccc(Cl)cc1Cl)-c1cccnc1 Show InChI InChI=1S/C14H9Cl2N5O/c15-9-3-4-10(11(16)6-9)13(22)21-14(17)19-12(20-21)8-2-1-5-18-7-8/h1-7H,(H2,17,19,20)	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC) Curated by ChEMBL					Assay Description Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assay				Bioorg Med Chem Lett 23: 4547-51 (2013) Article DOI: 10.1016/j.bmcl.2013.06.039 BindingDB Entry DOI: 10.7270/Q23B61JV
					More data for this Ligand-Target Pair