BDBM50440486 CHEMBL2426155

SMILES: CC(C)(C(c1ccccc1)c1ccn2cncc2c1)C(=O)Nc1nccs1

InChI Key: InChIKey=XHDKJGIOKHXSGM-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50440486 (CHEMBL2426155) Show SMILES CC(C)(C(c1ccccc1)c1ccn2cncc2c1)C(=O)Nc1nccs1 Show InChI InChI=1S/C21H20N4OS/c1-21(2,19(26)24-20-23-9-11-27-20)18(15-6-4-3-5-7-15)16-8-10-25-14-22-13-17(25)12-16/h3-14,18H,1-2H3,(H,23,24,26)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Binding affinity to glucocorticoid receptor-LBD (unknown origin) by fluorescence polarization assay				Bioorg Med Chem Lett 23: 5571-4 (2013) Article DOI: 10.1016/j.bmcl.2013.08.049 BindingDB Entry DOI: 10.7270/Q2QC04Z4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50440486 (CHEMBL2426155) Show SMILES CC(C)(C(c1ccccc1)c1ccn2cncc2c1)C(=O)Nc1nccs1 Show InChI InChI=1S/C21H20N4OS/c1-21(2,19(26)24-20-23-9-11-27-20)18(15-6-4-3-5-7-15)16-8-10-25-14-22-13-17(25)12-16/h3-14,18H,1-2H3,(H,23,24,26)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transrepression of glucocorticoid receptor in human A549 cells assessed as inhibition of PMA-induced AP-1 activity by luciferase reporter gene assay				Bioorg Med Chem Lett 23: 5571-4 (2013) Article DOI: 10.1016/j.bmcl.2013.08.049 BindingDB Entry DOI: 10.7270/Q2QC04Z4
					More data for this Ligand-Target Pair