BDBM50440723 CHEMBL2431073

SMILES: Cc1noc2[C@H](Cc3ncc[nH]3)N=C(c3c(C)c(C)sc3-c12)c1ccc(Cl)cc1

InChI Key: InChIKey=GWXIOJYNQZHICH-INIZCTEOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440723   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50440723 (CHEMBL2431073) Show SMILES Cc1noc2[C@H](Cc3ncc[nH]3)N=C(c3c(C)c(C)sc3-c12)c1ccc(Cl)cc1 |r,c:13| Show InChI InChI=1S/C22H19ClN4OS/c1-11-13(3)29-22-18(11)20(14-4-6-15(23)7-5-14)26-16(10-17-24-8-9-25-17)21-19(22)12(2)27-28-21/h4-9,16H,10H2,1-3H3,(H,24,25)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Constellation Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISA				ACS Med Chem Lett 4: 835-40 (2013) Article DOI: 10.1021/ml4001485 BindingDB Entry DOI: 10.7270/Q2DV1MB8
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50440723 (CHEMBL2431073) Show SMILES Cc1noc2[C@H](Cc3ncc[nH]3)N=C(c3c(C)c(C)sc3-c12)c1ccc(Cl)cc1 |r,c:13| Show InChI InChI=1S/C22H19ClN4OS/c1-11-13(3)29-22-18(11)20(14-4-6-15(23)7-5-14)26-16(10-17-24-8-9-25-17)21-19(22)12(2)27-28-21/h4-9,16H,10H2,1-3H3,(H,24,25)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Constellation Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrs				ACS Med Chem Lett 4: 835-40 (2013) Article DOI: 10.1021/ml4001485 BindingDB Entry DOI: 10.7270/Q2DV1MB8
					More data for this Ligand-Target Pair