BDBM50442176 CHEMBL2441598

SMILES: Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(cc2)-c2nnn[nH]2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F

InChI Key: InChIKey=AGFBRJLGKYFTAT-LJAQVGFWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442176   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2) (Homo sapiens (Human))	BDBM50442176 (CHEMBL2441598) Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(cc2)-c2nnn[nH]2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F |r,c:8| Show InChI InChI=1S/C31H26F6N6O3/c1-18-3-5-19(6-4-18)24-17-29(31(35,36)37,21-9-13-23(14-10-21)46-16-2-15-30(32,33)34)39-28(45)25(24)27(44)38-22-11-7-20(8-12-22)26-40-42-43-41-26/h3-14H,2,15-17H2,1H3,(H,38,44)(H,39,45)(H,40,41,42,43)/t29-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human MGAT2 by SPA assay				ACS Med Chem Lett 4: 898-9 (2013) Article DOI: 10.1021/ml400272q BindingDB Entry DOI: 10.7270/Q2WD421M
					More data for this Ligand-Target Pair
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2) (Homo sapiens (Human))	BDBM50442176 (CHEMBL2441598) Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(cc2)-c2nnn[nH]2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F |r,c:8| Show InChI InChI=1S/C31H26F6N6O3/c1-18-3-5-19(6-4-18)24-17-29(31(35,36)37,21-9-13-23(14-10-21)46-16-2-15-30(32,33)34)39-28(45)25(24)27(44)38-22-11-7-20(8-12-22)26-40-42-43-41-26/h3-14H,2,15-17H2,1H3,(H,38,44)(H,39,45)(H,40,41,42,43)/t29-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human MGAT2 by LC/MS assay				ACS Med Chem Lett 4: 898-9 (2013) Article DOI: 10.1021/ml400272q BindingDB Entry DOI: 10.7270/Q2WD421M
					More data for this Ligand-Target Pair