BDBM50442215 CHEMBL2441974

SMILES: OC(=O)C(=O)CC(=O)C=Cc1cn(Cc2ccc(O)cc2)c2ccccc12

InChI Key: InChIKey=GNPWHLCOLXMDNQ-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50442215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Terminal deoxynucleotidyltransferase (Homo sapiens (Human))	BDBM50442215 (CHEMBL2441974) Show SMILES OC(=O)C(=O)CC(=O)C=Cc1cn(Cc2ccc(O)cc2)c2ccccc12 |w:9.9| Show InChI InChI=1S/C21H17NO5/c23-16-8-5-14(6-9-16)12-22-13-15(18-3-1-2-4-19(18)22)7-10-17(24)11-20(25)21(26)27/h1-10,13,23H,11-12H2,(H,26,27)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Competitive inhibition of human TdT using TTP as substrate				J Med Chem 56: 7431-41 (2013) Article DOI: 10.1021/jm4010187 BindingDB Entry DOI: 10.7270/Q2H70H8G
					More data for this Ligand-Target Pair
Terminal deoxynucleotidyltransferase (Homo sapiens (Human))	BDBM50442215 (CHEMBL2441974) Show SMILES OC(=O)C(=O)CC(=O)C=Cc1cn(Cc2ccc(O)cc2)c2ccccc12 |w:9.9| Show InChI InChI=1S/C21H17NO5/c23-16-8-5-14(6-9-16)12-22-13-15(18-3-1-2-4-19(18)22)7-10-17(24)11-20(25)21(26)27/h1-10,13,23H,11-12H2,(H,26,27)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Non-competitive inhibition of human TdT using 3'-OH as substrate				J Med Chem 56: 7431-41 (2013) Article DOI: 10.1021/jm4010187 BindingDB Entry DOI: 10.7270/Q2H70H8G
					More data for this Ligand-Target Pair
DNA polymerase beta (Homo sapiens (Human))	BDBM50442215 (CHEMBL2441974) Show SMILES OC(=O)C(=O)CC(=O)C=Cc1cn(Cc2ccc(O)cc2)c2ccccc12 |w:9.9| Show InChI InChI=1S/C21H17NO5/c23-16-8-5-14(6-9-16)12-22-13-15(18-3-1-2-4-19(18)22)7-10-17(24)11-20(25)21(26)27/h1-10,13,23H,11-12H2,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant DNA polymerase beta				J Med Chem 56: 7431-41 (2013) Article DOI: 10.1021/jm4010187 BindingDB Entry DOI: 10.7270/Q2H70H8G
					More data for this Ligand-Target Pair