Found 3 hits for monomerid = 50445123 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50445123
(CHEMBL3103865)Show SMILES N[C@H]1CCCN(C1)c1ccncc1NC(=O)c1nc(ccc1N)-c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C23H23F3N6O/c24-23(25,26)16-6-2-1-5-15(16)18-8-7-17(28)21(30-18)22(33)31-19-12-29-10-9-20(19)32-11-3-4-14(27)13-32/h1-2,5-10,12,14H,3-4,11,13,27-28H2,(H,31,33)/t14-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description Inhibition of PIM1 (unknown origin) |
ACS Med Chem Lett 4: 1193-7 (2013)
Article DOI: 10.1021/ml400307j BindingDB Entry DOI: 10.7270/Q23X8840 |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50445123
(CHEMBL3103865)Show SMILES N[C@H]1CCCN(C1)c1ccncc1NC(=O)c1nc(ccc1N)-c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C23H23F3N6O/c24-23(25,26)16-6-2-1-5-15(16)18-8-7-17(28)21(30-18)22(33)31-19-12-29-10-9-20(19)32-11-3-4-14(27)13-32/h1-2,5-10,12,14H,3-4,11,13,27-28H2,(H,31,33)/t14-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description Inhibition of PIM3 (unknown origin) |
ACS Med Chem Lett 4: 1193-7 (2013)
Article DOI: 10.1021/ml400307j BindingDB Entry DOI: 10.7270/Q23X8840 |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human)) | BDBM50445123
(CHEMBL3103865)Show SMILES N[C@H]1CCCN(C1)c1ccncc1NC(=O)c1nc(ccc1N)-c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C23H23F3N6O/c24-23(25,26)16-6-2-1-5-15(16)18-8-7-17(28)21(30-18)22(33)31-19-12-29-10-9-20(19)32-11-3-4-14(27)13-32/h1-2,5-10,12,14H,3-4,11,13,27-28H2,(H,31,33)/t14-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description Inhibition of PIM2 (unknown origin) |
ACS Med Chem Lett 4: 1193-7 (2013)
Article DOI: 10.1021/ml400307j BindingDB Entry DOI: 10.7270/Q23X8840 |
More data for this Ligand-Target Pair | |