BindingDB PrimarySearch

BDBM50445475 CHEMBL3104854

SMILES: Cc1c2COC(=O)c2c(O)c(O)c1O

InChI Key: InChIKey=IREYRQPUBOQACQ-UHFFFAOYSA-N

Data: 13 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50445475
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50445475 (CHEMBL3104854) Show SMILES Cc1c2COC(=O)c2c(O)c(O)c1O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of AKT1 (unknown origin)				J Nat Prod 77: 49-56 (2014) Article DOI: 10.1021/np4005745 BindingDB Entry DOI: 10.7270/Q2X63PDV
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50445475 (CHEMBL3104854) Show SMILES Cc1c2COC(=O)c2c(O)c(O)c1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of IGF1R (unknown origin)				J Nat Prod 77: 49-56 (2014) Article DOI: 10.1021/np4005745 BindingDB Entry DOI: 10.7270/Q2X63PDV
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50445475 (CHEMBL3104854) Show SMILES Cc1c2COC(=O)c2c(O)c(O)c1O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of FAK (unknown origin)				J Nat Prod 77: 49-56 (2014) Article DOI: 10.1021/np4005745 BindingDB Entry DOI: 10.7270/Q2X63PDV
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50445475 (CHEMBL3104854) Show SMILES Cc1c2COC(=O)c2c(O)c(O)c1O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of AXL (unknown origin)				J Nat Prod 77: 49-56 (2014) Article DOI: 10.1021/np4005745 BindingDB Entry DOI: 10.7270/Q2X63PDV
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50445475 (CHEMBL3104854) Show SMILES Cc1c2COC(=O)c2c(O)c(O)c1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of aurora-B (unknown origin)				J Nat Prod 77: 49-56 (2014) Article DOI: 10.1021/np4005745 BindingDB Entry DOI: 10.7270/Q2X63PDV
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
NUAK family SNF1-like kinase 1 (Homo sapiens (Human))	BDBM50445475 (CHEMBL3104854) Show SMILES Cc1c2COC(=O)c2c(O)c(O)c1O Show InChI	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of ARK5 (unknown origin)				J Nat Prod 77: 49-56 (2014) Article DOI: 10.1021/np4005745 BindingDB Entry DOI: 10.7270/Q2X63PDV
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50445475 (CHEMBL3104854) Show SMILES Cc1c2COC(=O)c2c(O)c(O)c1O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of wild type MET (unknown origin)				J Nat Prod 77: 49-56 (2014) Article DOI: 10.1021/np4005745 BindingDB Entry DOI: 10.7270/Q2X63PDV
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase N1 (Homo sapiens (Human))	BDBM50445475 (CHEMBL3104854) Show SMILES Cc1c2COC(=O)c2c(O)c(O)c1O Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of PRK1 (unknown origin)				J Nat Prod 77: 49-56 (2014) Article DOI: 10.1021/np4005745 BindingDB Entry DOI: 10.7270/Q2X63PDV
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50445475 (CHEMBL3104854) Show SMILES Cc1c2COC(=O)c2c(O)c(O)c1O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of PLK1 (unknown origin)				J Nat Prod 77: 49-56 (2014) Article DOI: 10.1021/np4005745 BindingDB Entry DOI: 10.7270/Q2X63PDV
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50445475 (CHEMBL3104854) Show SMILES Cc1c2COC(=O)c2c(O)c(O)c1O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin)				J Nat Prod 77: 49-56 (2014) Article DOI: 10.1021/np4005745 BindingDB Entry DOI: 10.7270/Q2X63PDV
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase NEK6 (Homo sapiens (Human))	BDBM50445475 (CHEMBL3104854) Show SMILES Cc1c2COC(=O)c2c(O)c(O)c1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of NEK6 (unknown origin)				J Nat Prod 77: 49-56 (2014) Article DOI: 10.1021/np4005745 BindingDB Entry DOI: 10.7270/Q2X63PDV
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Nek2 (Homo sapiens (Human))	BDBM50445475 (CHEMBL3104854) Show SMILES Cc1c2COC(=O)c2c(O)c(O)c1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of NEK2 (unknown origin)				J Nat Prod 77: 49-56 (2014) Article DOI: 10.1021/np4005745 BindingDB Entry DOI: 10.7270/Q2X63PDV
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50445475 (CHEMBL3104854) Show SMILES Cc1c2COC(=O)c2c(O)c(O)c1O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of ALK (unknown origin)				J Nat Prod 77: 49-56 (2014) Article DOI: 10.1021/np4005745 BindingDB Entry DOI: 10.7270/Q2X63PDV
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					More data for this Ligand-Target Pair