BDBM50445737 CHEMBL3104395

SMILES: Cc1nc(sc1C(=O)NCc1ccccc1)-n1ccc(cc1=O)C(F)(F)F

InChI Key: InChIKey=KFNLQPPLNYTFSC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50445737   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stearoyl-CoA desaturase 1 (Homo sapiens (Human))	BDBM50445737 (CHEMBL3104395) Show SMILES Cc1nc(sc1C(=O)NCc1ccccc1)-n1ccc(cc1=O)C(F)(F)F Show InChI InChI=1S/C18H14F3N3O2S/c1-11-15(16(26)22-10-12-5-3-2-4-6-12)27-17(23-11)24-8-7-13(9-14(24)25)18(19,20)21/h2-9H,10H2,1H3,(H,22,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrate				Bioorg Med Chem Lett 24: 526-31 (2014) Article DOI: 10.1016/j.bmcl.2013.12.035 BindingDB Entry DOI: 10.7270/Q20003J1
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Mus musculus)	BDBM50445737 (CHEMBL3104395) Show SMILES Cc1nc(sc1C(=O)NCc1ccccc1)-n1ccc(cc1=O)C(F)(F)F Show InChI InChI=1S/C18H14F3N3O2S/c1-11-15(16(26)22-10-12-5-3-2-4-6-12)27-17(23-11)24-8-7-13(9-14(24)25)18(19,20)21/h2-9H,10H2,1H3,(H,22,26)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of SCD1 in mouse liver microsomes				Bioorg Med Chem Lett 24: 526-31 (2014) Article DOI: 10.1016/j.bmcl.2013.12.035 BindingDB Entry DOI: 10.7270/Q20003J1
					More data for this Ligand-Target Pair