BDBM50446110 CHEMBL3108849

SMILES: Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(C)c(F)c3)cc2)no1

InChI Key: InChIKey=JDFJXRQXDXETKA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phospho-1-fructokinase (Trypanosoma brucei)	BDBM50446110 (CHEMBL3108849) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(C)c(F)c3)cc2)no1 Show InChI InChI=1S/C19H18FN3O4S/c1-12-3-4-14(10-17(12)20)11-19(24)21-15-5-7-16(8-6-15)28(25,26)23-18-9-13(2)27-22-18/h3-10H,11H2,1-2H3,(H,21,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
6-phospho-1-fructokinase, putative (Trypanosoma cruzi)	BDBM50446110 (CHEMBL3108849) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(C)c(F)c3)cc2)no1 Show InChI InChI=1S/C19H18FN3O4S/c1-12-3-4-14(10-17(12)20)11-19(24)21-15-5-7-16(8-6-15)28(25,26)23-18-9-13(2)27-22-18/h3-10H,11H2,1-2H3,(H,21,24)(H,22,23)	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair