BDBM50448013 CHEMBL3115220

SMILES: Cn1cc(nn1)S(=O)(=O)N1CC2CCC(NC(=O)c3ccc(Cl)cc3Cl)C2C1

InChI Key: InChIKey=OACBZHMUMSVRTK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448013   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50448013 (CHEMBL3115220) Show SMILES Cn1cc(nn1)S(=O)(=O)N1CC2CCC(NC(=O)c3ccc(Cl)cc3Cl)C2C1 Show InChI InChI=1S/C17H19Cl2N5O3S/c1-23-9-16(21-22-23)28(26,27)24-7-10-2-5-15(13(10)8-24)20-17(25)12-4-3-11(18)6-14(12)19/h3-4,6,9-10,13,15H,2,5,7-8H2,1H3,(H,20,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of GlyT1 (unknown origin) assessed as [14C]-glycine transport				Bioorg Med Chem Lett 24: 1062-6 (2014) Article DOI: 10.1016/j.bmcl.2014.01.011 BindingDB Entry DOI: 10.7270/Q2XD1350
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50448013 (CHEMBL3115220) Show SMILES Cn1cc(nn1)S(=O)(=O)N1CC2CCC(NC(=O)c3ccc(Cl)cc3Cl)C2C1 Show InChI InChI=1S/C17H19Cl2N5O3S/c1-23-9-16(21-22-23)28(26,27)24-7-10-2-5-15(13(10)8-24)20-17(25)12-4-3-11(18)6-14(12)19/h3-4,6,9-10,13,15H,2,5,7-8H2,1H3,(H,20,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of GlyT2 (unknown origin) assessed as [14C]-glycine transport				Bioorg Med Chem Lett 24: 1062-6 (2014) Article DOI: 10.1016/j.bmcl.2014.01.011 BindingDB Entry DOI: 10.7270/Q2XD1350
					More data for this Ligand-Target Pair