null
SMILES: Cc1ccc(cc1Cl)-n1nnnc1NCc1ccco1
InChI Key: InChIKey=AOISOZNDVQJYQF-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA gyrase subunit A/B (Staphylococcus aureus) | BDBM50449892![]() (CHEMBL4167345) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Warsaw Curated by ChEMBL | Assay Description Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity using pBR322 DNA as substrate after 30 mins by ethidium bromide staining based a... | Eur J Med Chem 156: 631-640 (2018) Article DOI: 10.1016/j.ejmech.2018.07.041 BindingDB Entry DOI: 10.7270/Q2VQ357Z | |||||||||||
More data for this Ligand-Target Pair |