BDBM50451034 CHEMBL4208998

SMILES: CNC(=O)c1cc(Oc2ccc(cc2)C2=NNC(C2)c2ccc(OC)cc2)ccn1

InChI Key: InChIKey=AWMXNRTWEPBRNZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50451034 (CHEMBL4208998) Show SMILES CNC(=O)c1cc(Oc2ccc(cc2)C2=NNC(C2)c2ccc(OC)cc2)ccn1 |t:15| Show InChI InChI=1S/C23H22N4O3/c1-24-23(28)22-13-19(11-12-25-22)30-18-9-5-16(6-10-18)21-14-20(26-27-21)15-3-7-17(29-2)8-4-15/h3-13,20,26H,14H2,1-2H3,(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins using FAM-labeled peptide and ATP by mobility shift assay				Bioorg Med Chem 25: 5754-5763 (2017) Article DOI: 10.1016/j.bmc.2017.09.003 BindingDB Entry DOI: 10.7270/Q2057JGW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50451034 (CHEMBL4208998) Show SMILES CNC(=O)c1cc(Oc2ccc(cc2)C2=NNC(C2)c2ccc(OC)cc2)ccn1 |t:15| Show InChI InChI=1S/C23H22N4O3/c1-24-23(28)22-13-19(11-12-25-22)30-18-9-5-16(6-10-18)21-14-20(26-27-21)15-3-7-17(29-2)8-4-15/h3-13,20,26H,14H2,1-2H3,(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of BRAF (unknown origin) incubated for 10 mins using FAM-labeled peptide and ATP by mobility shift assay				Bioorg Med Chem 25: 5754-5763 (2017) Article DOI: 10.1016/j.bmc.2017.09.003 BindingDB Entry DOI: 10.7270/Q2057JGW
					More data for this Ligand-Target Pair