BDBM50452011 CHEMBL2110188

SMILES: O=C1[C@H](Cc2ccccc2CN1c1ccccc1)NCc1cncn1Cc1ccc(cc1)C#N

InChI Key: InChIKey=DZJIZUHWPKFMQZ-MHZLTWQESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50452011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50452011 (CHEMBL2110188) Show SMILES O=C1[C@H](Cc2ccccc2CN1c1ccccc1)NCc1cncn1Cc1ccc(cc1)C#N |r| Show InChI InChI=1S/C28H25N5O/c29-15-21-10-12-22(13-11-21)18-32-20-30-16-26(32)17-31-27-14-23-6-4-5-7-24(23)19-33(28(27)34)25-8-2-1-3-9-25/h1-13,16,20,27,31H,14,17-19H2/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of farnesyltransferase				Bioorg Med Chem Lett 14: 767-71 (2004) BindingDB Entry DOI: 10.7270/Q2348JSW
					More data for this Ligand-Target Pair