null

SMILES: COC(=O)Cc1cc(NCc2cc(O)ccc2O)ccc1O

InChI Key: InChIKey=GHQGQYAVVLRDHS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50453580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50453580 (CHEMBL355461) Show SMILES COC(=O)Cc1cc(NCc2cc(O)ccc2O)ccc1O Show InChI InChI=1S/C16H17NO5/c1-22-16(21)8-10-6-12(2-4-14(10)19)17-9-11-7-13(18)3-5-15(11)20/h2-7,17-20H,8-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
U266 INSERM-URA D1500 CNRS Curated by ChEMBL					Assay Description Inhibition of EGF-stimulated DNA synthesis in ER22 cells, by measuring [3H]Me-dT incorporation into ER 22 cells				J Med Chem 37: 845-59 (1994) BindingDB Entry DOI: 10.7270/Q2QV3KJ3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50453580 (CHEMBL355461) Show SMILES COC(=O)Cc1cc(NCc2cc(O)ccc2O)ccc1O Show InChI InChI=1S/C16H17NO5/c1-22-16(21)8-10-6-12(2-4-14(10)19)17-9-11-7-13(18)3-5-15(11)20/h2-7,17-20H,8-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
U266 INSERM-URA D1500 CNRS Curated by ChEMBL					Assay Description Inhibitory potency against protein tyrosine kinase activity associated with EGFR was evaluated using ER 22 cell membrane				J Med Chem 37: 845-59 (1994) BindingDB Entry DOI: 10.7270/Q2QV3KJ3
					More data for this Ligand-Target Pair