BDBM50454327 CHEMBL4211659
SMILES: CC(C)(C)c1ccc(cc1)-c1cc(C(=O)N2CCN(CC2)C(=O)Nc2ccc(cc2)C(F)(F)F)c2ccccc2n1
InChI Key: InChIKey=GIYSYHUYNCPTDG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50454327 (CHEMBL4211659) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced intracellular calcium level preincubated for 2.5 mins followed by caps... | Bioorg Med Chem 26: 845-854 (2018) Article DOI: 10.1016/j.bmc.2017.12.048 BindingDB Entry DOI: 10.7270/Q27S7RDV | |||||||||||
More data for this Ligand-Target Pair |