BDBM50454327 CHEMBL4211659

SMILES: CC(C)(C)c1ccc(cc1)-c1cc(C(=O)N2CCN(CC2)C(=O)Nc2ccc(cc2)C(F)(F)F)c2ccccc2n1

InChI Key: InChIKey=GIYSYHUYNCPTDG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50454327 (CHEMBL4211659) Show SMILES CC(C)(C)c1ccc(cc1)-c1cc(C(=O)N2CCN(CC2)C(=O)Nc2ccc(cc2)C(F)(F)F)c2ccccc2n1 Show InChI InChI=1S/C32H31F3N4O2/c1-31(2,3)22-10-8-21(9-11-22)28-20-26(25-6-4-5-7-27(25)37-28)29(40)38-16-18-39(19-17-38)30(41)36-24-14-12-23(13-15-24)32(33,34)35/h4-15,20H,16-19H2,1-3H3,(H,36,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced intracellular calcium level preincubated for 2.5 mins followed by caps...				Bioorg Med Chem 26: 845-854 (2018) Article DOI: 10.1016/j.bmc.2017.12.048 BindingDB Entry DOI: 10.7270/Q27S7RDV
					More data for this Ligand-Target Pair