BDBM50456403 CHEMBL4213252

SMILES: [O-][N+](=O)c1ccc2oc(=O)n(Cc3ccc(Cl)cc3)c2c1

InChI Key: InChIKey=OETPBWKSXZCOLF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50456403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50456403 (CHEMBL4213252) Show SMILES [O-][N+](=O)c1ccc2oc(=O)n(Cc3ccc(Cl)cc3)c2c1 Show InChI InChI=1S/C14H9ClN2O4/c15-10-3-1-9(2-4-10)8-16-12-7-11(17(19)20)5-6-13(12)21-14(16)18/h1-7H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs				Eur J Med Chem 138: 199-211 (2017) Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012
					More data for this Ligand-Target Pair