BDBM50461185 CHEMBL4225148
SMILES: CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCCNC(=O)CCCCCCCCC
InChI Key: InChIKey=JXHLVIPKHULGLV-WVIMUZHZSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Toll-like receptor 2 (Mus musculus) | BDBM50461185 (CHEMBL4225148) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University Curated by ChEMBL | Assay Description Inhibition of biotin labelled Pam2CSK4 binding to mouse TLR2 Fc chimera protein after 45 mins by AlphaScreen assay | Bioorg Med Chem Lett 28: 1638-1641 (2018) Article DOI: 10.1016/j.bmcl.2018.03.042 BindingDB Entry DOI: 10.7270/Q2CC139G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 2 (TLR2) (Homo sapiens (Human)) | BDBM50461185 (CHEMBL4225148) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University Curated by ChEMBL | Assay Description Inhibition of biotin labelled Pam2CSK4 binding to His tagged human TLR2 after 45 mins by AlphaScreen assay | Bioorg Med Chem Lett 28: 1638-1641 (2018) Article DOI: 10.1016/j.bmcl.2018.03.042 BindingDB Entry DOI: 10.7270/Q2CC139G | |||||||||||
More data for this Ligand-Target Pair |