BDBM50462210 CHEMBL4238271

SMILES: C[C@@H](O)[C@@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CSSC[C@H](NC(=O)CNC1=O)C(N)=O)NC(C)=O

InChI Key: InChIKey=WTPLHKNIXTZVGF-VRIFGJDVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50462210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kelch-like ECH-associated protein 1 (Homo sapiens (Human))	BDBM50462210 (CHEMBL4238271) Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CSSC[C@H](NC(=O)CNC1=O)C(N)=O)NC(C)=O |r| Show InChI InChI=1S/C24H37N7O12S2/c1-10(32)19-24(43)26-7-16(34)28-14(20(25)39)8-44-45-9-15(27-11(2)33)23(42)30-12(3-5-17(35)36)21(40)29-13(22(41)31-19)4-6-18(37)38/h10,12-15,19,32H,3-9H2,1-2H3,(H2,25,39)(H,26,43)(H,27,33)(H,28,34)(H,29,40)(H,30,42)(H,31,41)(H,35,36)(H,37,38)/t10-,12+,13+,14+,15+,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.52E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of East Anglia Curated by ChEMBL					Assay Description Displacement of F-14 from Keap1 Kelch domain (unknown origin) expressed in Escherichia coli BL21 (DE3) after 15 mins by fluorescence polarization ass...				Bioorg Med Chem Lett 28: 2728-2731 (2018) Article DOI: 10.1016/j.bmcl.2018.03.003 BindingDB Entry DOI: 10.7270/Q2QC065N
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