Found 3 hits for monomerid = 50462240 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histone deacetylase
(Homo sapiens (Human)) | BDBM50462240
![PNG](/data/jpeg/tenK5046/BindingDB_50462240.png) (CHEMBL4249195)Show SMILES CC(C)c1cc(C(=O)N2CCc3cc(NC(=O)CCC(=O)NO)ccc23)c(O)cc1O Show InChI InChI=1S/C22H25N3O6/c1-12(2)15-10-16(19(27)11-18(15)26)22(30)25-8-7-13-9-14(3-4-17(13)25)23-20(28)5-6-21(29)24-31/h3-4,9-12,26-27,31H,5-8H2,1-2H3,(H,23,28)(H,24,29) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Taipei Medical University
Curated by ChEMBL
| Assay Description Inhibition of HDAC in human HeLa nuclear extract using Ac-Lys(Ac)-pNA as substrate measured after 30 mins by fluorometric analysis |
Eur J Med Chem 150: 667-677 (2018)
Article DOI: 10.1016/j.ejmech.2018.03.006 BindingDB Entry DOI: 10.7270/Q2XW4NGM |
More data for this Ligand-Target Pair | |
Heat shock protein HSP 90-alpha
(Homo sapiens (Human)) | BDBM50462240
![PNG](/data/jpeg/tenK5046/BindingDB_50462240.png) (CHEMBL4249195)Show SMILES CC(C)c1cc(C(=O)N2CCc3cc(NC(=O)CCC(=O)NO)ccc23)c(O)cc1O Show InChI InChI=1S/C22H25N3O6/c1-12(2)15-10-16(19(27)11-18(15)26)22(30)25-8-7-13-9-14(3-4-17(13)25)23-20(28)5-6-21(29)24-31/h3-4,9-12,26-27,31H,5-8H2,1-2H3,(H,23,28)(H,24,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Taipei Medical University
Curated by ChEMBL
| Assay Description Inhibition of FITC-geldanamycin binding to HSP90alpha (unknown origin) after 3 hrs by fluorescence polarization assay |
Eur J Med Chem 150: 667-677 (2018)
Article DOI: 10.1016/j.ejmech.2018.03.006 BindingDB Entry DOI: 10.7270/Q2XW4NGM |
More data for this Ligand-Target Pair | |
Cereblon/Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50462240
![PNG](/data/jpeg/tenK5046/BindingDB_50462240.png) (CHEMBL4249195)Show SMILES CC(C)c1cc(C(=O)N2CCc3cc(NC(=O)CCC(=O)NO)ccc23)c(O)cc1O Show InChI InChI=1S/C22H25N3O6/c1-12(2)15-10-16(19(27)11-18(15)26)22(30)25-8-7-13-9-14(3-4-17(13)25)23-20(28)5-6-21(29)24-31/h3-4,9-12,26-27,31H,5-8H2,1-2H3,(H,23,28)(H,24,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Taipei Medical University
Curated by ChEMBL
| Assay Description Inhibition of human HDAC6 using RHKK(Ac) as substrate |
Eur J Med Chem 150: 667-677 (2018)
Article DOI: 10.1016/j.ejmech.2018.03.006 BindingDB Entry DOI: 10.7270/Q2XW4NGM |
More data for this Ligand-Target Pair | |