BDBM50463109 CHEMBL4241418

SMILES: CC(C)(C)C(=O)N1CCN(CC1)c1ccc(NC(=O)c2cccnc2)cc1Cl

InChI Key: InChIKey=XLLWEIMFRZNCGR-UHFFFAOYSA-N

Data: 1 KI  1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463109   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA repair protein REV1 (Homo sapiens)	BDBM50463109 (CHEMBL4241418) Show SMILES CC(C)(C)C(=O)N1CCN(CC1)c1ccc(NC(=O)c2cccnc2)cc1Cl Show InChI InChI=1S/C21H25ClN4O2/c1-21(2,3)20(28)26-11-9-25(10-12-26)18-7-6-16(13-17(18)22)24-19(27)15-5-4-8-23-14-15/h4-8,13-14H,9-12H2,1-3H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...				Bioorg Med Chem 26: 4301-4309 (2018) Article DOI: 10.1016/j.bmc.2018.07.029 BindingDB Entry DOI: 10.7270/Q2K93B5H
					More data for this Ligand-Target Pair
DNA repair protein REV1 (Homo sapiens)	BDBM50463109 (CHEMBL4241418) Show SMILES CC(C)(C)C(=O)N1CCN(CC1)c1ccc(NC(=O)c2cccnc2)cc1Cl Show InChI InChI=1S/C21H25ClN4O2/c1-21(2,3)20(28)26-11-9-25(10-12-26)18-7-6-16(13-17(18)22)24-19(27)15-5-4-8-23-14-15/h4-8,13-14H,9-12H2,1-3H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...				Bioorg Med Chem 26: 4301-4309 (2018) Article DOI: 10.1016/j.bmc.2018.07.029 BindingDB Entry DOI: 10.7270/Q2K93B5H
					More data for this Ligand-Target Pair
DNA repair protein REV1 (Homo sapiens)	BDBM50463109 (CHEMBL4241418) Show SMILES CC(C)(C)C(=O)N1CCN(CC1)c1ccc(NC(=O)c2cccnc2)cc1Cl Show InChI InChI=1S/C21H25ClN4O2/c1-21(2,3)20(28)26-11-9-25(10-12-26)18-7-6-16(13-17(18)22)24-19(27)15-5-4-8-23-14-15/h4-8,13-14H,9-12H2,1-3H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...				Bioorg Med Chem 26: 4301-4309 (2018) Article DOI: 10.1016/j.bmc.2018.07.029 BindingDB Entry DOI: 10.7270/Q2K93B5H
					More data for this Ligand-Target Pair