BDBM50463715 CHEMBL4243470

SMILES: Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cc(C)nc3noc(N)c23)c1

InChI Key: InChIKey=UFSGCADQVRKELP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50463715 (CHEMBL4243470) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cc(C)nc3noc(N)c23)c1 Show InChI InChI=1S/C21H19N5O2/c1-12-4-3-5-16(10-12)25-21(27)24-15-8-6-14(7-9-15)17-11-13(2)23-20-18(17)19(22)28-26-20/h3-11H,22H2,1-2H3,(H2,24,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human FLT3 using biotin labeled substrate after 1 hr by HTFR assay				Bioorg Med Chem 26: 4735-4744 (2018) Article DOI: 10.1016/j.bmc.2018.08.013 BindingDB Entry DOI: 10.7270/Q208680Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50463715 (CHEMBL4243470) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cc(C)nc3noc(N)c23)c1 Show InChI InChI=1S/C21H19N5O2/c1-12-4-3-5-16(10-12)25-21(27)24-15-8-6-14(7-9-15)17-11-13(2)23-20-18(17)19(22)28-26-20/h3-11H,22H2,1-2H3,(H2,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta using biotin labeled substrate after 1 hr by HTFR assay				Bioorg Med Chem 26: 4735-4744 (2018) Article DOI: 10.1016/j.bmc.2018.08.013 BindingDB Entry DOI: 10.7270/Q208680Z
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50463715 (CHEMBL4243470) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cc(C)nc3noc(N)c23)c1 Show InChI InChI=1S/C21H19N5O2/c1-12-4-3-5-16(10-12)25-21(27)24-15-8-6-14(7-9-15)17-11-13(2)23-20-18(17)19(22)28-26-20/h3-11H,22H2,1-2H3,(H2,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human KDR using biotin labeled substrate after 1 hr by HTFR assay				Bioorg Med Chem 26: 4735-4744 (2018) Article DOI: 10.1016/j.bmc.2018.08.013 BindingDB Entry DOI: 10.7270/Q208680Z
					More data for this Ligand-Target Pair