BDBM50464238 CHEMBL4287695

SMILES: O=S(=O)(N1CCN(CC1)c1ccccc1)c1ccc2OCOc2c1

InChI Key: InChIKey=UUQPVOSOSQITKE-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464238   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine receptor alpha-3/beta (Homo sapiens (Human))	BDBM50464238 (CHEMBL4287695) Show SMILES O=S(=O)(N1CCN(CC1)c1ccccc1)c1ccc2OCOc2c1 Show InChI InChI=1S/C17H18N2O4S/c20-24(21,15-6-7-16-17(12-15)23-13-22-16)19-10-8-18(9-11-19)14-4-2-1-3-5-14/h1-7,12H,8-11,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair