BDBM50464544 CHEMBL4281698

SMILES: Fc1cc(NC(=O)c2cc3cccnc3n(-c3ccc(Cl)cc3)c2=O)ccc1Oc1ccnc2[nH]ccc12

InChI Key: InChIKey=CAPSXEZVHVEZGN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464544   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50464544 (CHEMBL4281698) Show SMILES Fc1cc(NC(=O)c2cc3cccnc3n(-c3ccc(Cl)cc3)c2=O)ccc1Oc1ccnc2[nH]ccc12 Show InChI InChI=1S/C28H17ClFN5O3/c29-17-3-6-19(7-4-17)35-26-16(2-1-11-33-26)14-21(28(35)37)27(36)34-18-5-8-24(22(30)15-18)38-23-10-13-32-25-20(23)9-12-31-25/h1-15H,(H,31,32)(H,34,36)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of cMET (unknown origin) using poly(Glu,Tyr) 4:1 substrate after 30 mins by HTFR analysis				Eur J Med Chem 143: 266-275 (2018) Article DOI: 10.1016/j.ejmech.2017.11.034 BindingDB Entry DOI: 10.7270/Q2JW8HJZ
					More data for this Ligand-Target Pair