BDBM50466164 CHEMBL4283474
SMILES: Fc1cc(F)c(C(=O)Nc2cncc(c2)-c2cc(cs2)-c2cccnc2)c(F)c1
InChI Key: InChIKey=WCJBJECTLLTBHS-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human)) | BDBM50466164 (CHEMBL4283474) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 299 | n/a | n/a | n/a | n/a | n/a | n/a |
German University in Cairo Curated by ChEMBL | Assay Description Inhibition of recombinant full length human Dyrk1B expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP | Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM50466164 (CHEMBL4283474) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
German University in Cairo Curated by ChEMBL | Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP | Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q | |||||||||||
More data for this Ligand-Target Pair |