BDBM50468143 CHEMBL4281446

SMILES: OC(=O)c1ccc(cc1)N1CC2(CCN(Cc3ccc(c(c3)C3CC3)C(F)(F)F)CC2)OC1=O

InChI Key: InChIKey=GOJNWMYTALIYDL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50468143 (CHEMBL4281446) Show SMILES OC(=O)c1ccc(cc1)N1CC2(CCN(Cc3ccc(c(c3)C3CC3)C(F)(F)F)CC2)OC1=O Show InChI InChI=1S/C25H25F3N2O4/c26-25(27,28)21-8-1-16(13-20(21)17-2-3-17)14-29-11-9-24(10-12-29)15-30(23(33)34-24)19-6-4-18(5-7-19)22(31)32/h1,4-8,13,17H,2-3,9-12,14-15H2,(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranes				ACS Med Chem Lett 9: 1088-1093 (2018) Article DOI: 10.1021/acsmedchemlett.8b00306 BindingDB Entry DOI: 10.7270/Q2V127H3
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50468143 (CHEMBL4281446) Show SMILES OC(=O)c1ccc(cc1)N1CC2(CCN(Cc3ccc(c(c3)C3CC3)C(F)(F)F)CC2)OC1=O Show InChI InChI=1S/C25H25F3N2O4/c26-25(27,28)21-8-1-16(13-20(21)17-2-3-17)14-29-11-9-24(10-12-29)15-30(23(33)34-24)19-6-4-18(5-7-19)22(31)32/h1,4-8,13,17H,2-3,9-12,14-15H2,(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...				ACS Med Chem Lett 9: 1088-1093 (2018) Article DOI: 10.1021/acsmedchemlett.8b00306 BindingDB Entry DOI: 10.7270/Q2V127H3
					More data for this Ligand-Target Pair
Somatostatin receptor (Mus musculus)	BDBM50468143 (CHEMBL4281446) Show SMILES OC(=O)c1ccc(cc1)N1CC2(CCN(Cc3ccc(c(c3)C3CC3)C(F)(F)F)CC2)OC1=O Show InChI InChI=1S/C25H25F3N2O4/c26-25(27,28)21-8-1-16(13-20(21)17-2-3-17)14-29-11-9-24(10-12-29)15-30(23(33)34-24)19-6-4-18(5-7-19)22(31)32/h1,4-8,13,17H,2-3,9-12,14-15H2,(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Antagonist activity at mouse SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...				ACS Med Chem Lett 9: 1088-1093 (2018) Article DOI: 10.1021/acsmedchemlett.8b00306 BindingDB Entry DOI: 10.7270/Q2V127H3
					More data for this Ligand-Target Pair