BDBM50468586 CHEMBL4277166

SMILES: NC(=O)c1ccc(Oc2ccccc2F)cc1

InChI Key: InChIKey=PFSGBISBXBLFEY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50468586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 10 (Homo sapiens (Human))	BDBM50468586 (CHEMBL4277166) Show SMILES NC(=O)c1ccc(Oc2ccccc2F)cc1 Show InChI InChI=1S/C13H10FNO2/c14-11-3-1-2-4-12(11)17-10-7-5-9(6-8-10)13(15)16/h1-8H,(H2,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 1...				Eur J Med Chem 156: 93-102 (2018) Article DOI: 10.1016/j.ejmech.2018.06.047 BindingDB Entry DOI: 10.7270/Q2P271SW
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 10 (Homo sapiens (Human))	BDBM50468586 (CHEMBL4277166) Show SMILES NC(=O)c1ccc(Oc2ccccc2F)cc1 Show InChI InChI=1S/C13H10FNO2/c14-11-3-1-2-4-12(11)17-10-7-5-9(6-8-10)13(15)16/h1-8H,(H2,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 1...				Eur J Med Chem 156: 93-102 (2018) Article DOI: 10.1016/j.ejmech.2018.06.047 BindingDB Entry DOI: 10.7270/Q2P271SW
					More data for this Ligand-Target Pair