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SMILES: CS(=O)(=O)c1cccc(c1)N1c2ccccc2SC(CC1=O)c1ccc(cc1)C(=O)NCc1cccc(Cl)c1

InChI Key: InChIKey=BKYZIUBTGVPVNB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50469283   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))		BDBM50469283
PNG
(CHEMBL4284111)
Show SMILES CS(=O)(=O)c1cccc(c1)N1c2ccccc2SC(CC1=O)c1ccc(cc1)C(=O)NCc1cccc(Cl)c1
Show InChI InChI=1S/C30H25ClN2O4S2/c1-39(36,37)25-9-5-8-24(17-25)33-26-10-2-3-11-27(26)38-28(18-29(33)34)21-12-14-22(15-13-21)30(35)32-19-20-6-4-7-23(31)16-20/h2-17,28H,18-19H2,1H3,(H,32,35)
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PC cid
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Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant N-terminal His6-tagged human GSK-3beta expressed in Baculovirus infected SF9 cells using prephosphorylated-GS2 polype...

Bioorg Med Chem 26: 5479-5493 (2018)


Article DOI: 10.1016/j.bmc.2018.09.027
BindingDB Entry DOI: 10.7270/Q2319ZMZ
More data for this
Ligand-Target Pair