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BDBM50470505 CHEMBL4279641

SMILES: Oc1cc(O)c2sc3nc(cc(-c4cccs4)c3c2n1)-c1cccs1

InChI Key: InChIKey=ZZAIXNUGEDHPDY-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470505   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase KAT8


(Homo sapiens (Human))		BDBM50470505
PNG
(CHEMBL4279641)
Show SMILES Oc1cc(O)c2sc3nc(cc(-c4cccs4)c3c2n1)-c1cccs1
Show InChI InChI=1S/C18H10N2O2S3/c21-11-8-14(22)20-16-15-9(12-3-1-5-23-12)7-10(13-4-2-6-24-13)19-18(15)25-17(11)16/h1-8H,(H2,20,21,22)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human His-tagged MOF preincubated for 10 mins followed by biotin-labeled H4K16 substrate addition measured after 30 mins in presence of...

Eur J Med Chem 157: 867-876 (2018)


Article DOI: 10.1016/j.ejmech.2018.08.026
BindingDB Entry DOI: 10.7270/Q2CC13DT
More data for this
Ligand-Target Pair