BDBM50470565 CHEMBL4276670

SMILES: Nc1nc(F)nc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@@H]1O

InChI Key: InChIKey=JUQZSESVGXFBBE-UHTZMRCNSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50470565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-nucleotidase (Homo sapiens (Human))	BDBM50470565 (CHEMBL4276670) Show SMILES Nc1nc(F)nc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C11H16FN5O9P2/c12-11-15-8(13)5-9(16-11)17(2-14-5)10-7(19)6(18)4(26-10)1-25-28(23,24)3-27(20,21)22/h2,4,6-7,10,18-19H,1,3H2,(H,23,24)(H2,13,15,16)(H2,20,21,22)/t4-,6-,7+,10-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Claude Bernard Lyon 1 Curated by ChEMBL					Assay Description Inhibition of CD73 in human MDA-MB-231 cells assessed as reduction in conversion of AMP to adenosine incubated for 30 mins by malachite green reagent...				Eur J Med Chem 157: 1051-1055 (2018) Article DOI: 10.1016/j.ejmech.2018.08.035 BindingDB Entry DOI: 10.7270/Q2QJ7M16
					More data for this Ligand-Target Pair
5'-nucleotidase (Homo sapiens (Human))	BDBM50470565 (CHEMBL4276670) Show SMILES Nc1nc(F)nc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C11H16FN5O9P2/c12-11-15-8(13)5-9(16-11)17(2-14-5)10-7(19)6(18)4(26-10)1-25-28(23,24)3-27(20,21)22/h2,4,6-7,10,18-19H,1,3H2,(H,23,24)(H2,13,15,16)(H2,20,21,22)/t4-,6-,7+,10-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Claude Bernard Lyon 1 Curated by ChEMBL					Assay Description Inhibition of CD73 in human NCI-H292 cells assessed as reduction in conversion of AMP to adenosine incubated for 30 mins by malachite green reagent b...				Eur J Med Chem 157: 1051-1055 (2018) Article DOI: 10.1016/j.ejmech.2018.08.035 BindingDB Entry DOI: 10.7270/Q2QJ7M16
					More data for this Ligand-Target Pair